IUI stands for intrauterine insemination. A special catheter is used to place a concentrated amount of washed sperm directly into the uterus around the time of ovulation. The goal of IUI is to increase the number of sperms that reach the egg and subsequently increase the chance of fertilization.
IUI can be performed either in a natural cycle or a stimulated cycle. Ovulation induction involves stimulating the ovary to produce one or more eggs. For ovulation induction you might need to take tablets alone or tablets plus HMG injections to boost the oocyte (egg) growth.
After you have taken ovulation induction medicines, the response of ovaries need to be monitored. It is done to measure the growth of follicles. Type and doses of drug is calculated accordingly on individual basis to obtain optimum ovulation and to prevent side-effects. Usually folliculometry is done by transvaginal ultrasound scanning. [Two to three times or more during a treatment cycle] .When the leading follicle measures > 17mm in diameter and the endometrium is well developed, an HCG injection is given to trigger maturity of the oocyte and ovulation. Insemination is done when ovulation is imminent or just after.
Procedure for insemination is very simple, fast and painless. It involves insertion of a speculum into the vagina to visualize the cervix and then cervix is cleaned with culture medium. The prepared sperm is then injected into the cavity of the womb using a fine plastic catheter. After insemination little rest for patient is advisable.
Implantation can take place anywhere from 6 to 12 days after ovulation to occur. Thus pregnancy test for hormone ? hCG should be done at least two weeks after the IUI procedure. Confirmation of pregnancy should be done by ultrasound scan for fetal heart after 4 weeks.
The success rate depends on the age of the woman conceiving. It also depends on the reason of infertility and the number of washed sperm that actually made up the concentrated volume. IUI’s success rate is around from 10 to 30% per cycle, keeping in mind various factors that affect conception.